Finding Antitubercular Leads from Marine-Derived and Entomopathogenic Fung
نویسندگان
چکیده
The occurrence of Mycobacterium tuberculosis resistance encourages the discovery new antitubercular candidates. Microbes including fungi and bacteria are well known reservoir for isolating antibiotic compounds, among natural product resources. In this review, we report promising compounds from marine-derived entomopathogenic fungi, reported 2000 to 2022. A comprehensive literature search was conducted through scientific websites, Google Scholar, Springer, Pubmed. Eighty-three were reported, where 57 them derived associated with marine ecosystem. Those belong 10 fungal genera. remaining active isolated 7 genera fungi. Gliotoxin, 12,13-dihydroxy-fumitremorgin, helvolic acid as hirsutellones A-D bioactive their remarkable activity, which be investigated further in leads. Deeper investigation on these might candidates future.
 Keywords: Antitubercular; fungi; Mycobaterium tuberculosis; secondary metabolites
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ژورنال
عنوان ژورنال: Jurnal Farmasi Udayana
سال: 2023
ISSN: ['2301-7716', '2622-4607']
DOI: https://doi.org/10.24843/jfu.2023.v12.i01.p09